This is minor, but... on your main top nav buttons, they look like pull down menus to me, and I hover over them waiting for the pull down menus that never come. Perhaps you could add some simple rollover effect to visually clue me in to the fact that I am on an active nav link (like change the text to black or something).
Also, on your "Search" page, the content area on the right is hot pink, making the red "Search Profiles" graphic header look bad. I think this was probably supposed to be a white background (I'm in IE6).