No. It has to be interpreted though mod_rewrite.
The problem is, when you try and request domain.com/something/title_of_value1.html without using mod_rewrite, apache automatically sends back a 404 error.
Now, you could have your 404 page be a 404.php page, that interprets the url and parses what it needs to, but that's not really URL friend or search engine friendly, because a 404 error still gets sent back.
So, search engines will never index the page with this method, making it totally useless.
Mod_rewrite is not that hard. You can use it in the .htaccess file in the same directory as the php file.
Here's a rule generator:
http://www.webmaster-toolkit.com/mod...enerator.shtml