BioMail is a small web-based application for medical researchers and biologists. It is written to automate searching for recent scientific papers in the PubMed Medline database. Periodically BioMail does a user-customized Medline search and sends all matching articles recently added to Medline to the users' e-mail address. HTML-formatted e-mails generated by BioMail can be used to show selected references in medline format, which is compatible with EndNote reference manager.