This article explores the N-tier and Distributed Application Architecture. Over the last decade, the way applications are designed has evolved and come a long way. We have stand-alone applications, server based applications, client server applications, web based applications, n-tier applications, distributed applications, Peer-to-peer apps, service-oriented Architectures, component based Development and the list goes on. This article discusses the advantages, disadvantages of n-tier applications and methods to implement web based n-tier Applications using C#, .NET